Aims. To characterize the population of drug users consulting the Emer
gency Room (ER) of a university hospital with acute opiate overdose (A
OO) and to assess rate of referral to specialized treatment programme.
Design. Survey of a 12-month sample of AOO patients. Measurements. Me
dical and psychosocial features of the drug users, details of emergenc
y treatment and referral by a mobile resuscitation ream (SMUR) and the
ER of our hospital (CHUV-Lausanne, Switzerland). In addition fatal AO
O cases were collected by the Institute of Forensic Medicine (IFM) dur
ing the same period. Findings. One hundred and eighty-four cases of AO
O (134 patients) were treated. The files of the IFM detailed six addit
ional deceased cases. This population of drug users was characterized
by an over-representation of men (73%), by young age (27.4 years), by
a high rate of multi-drugs use (90%) and by a high rate of multiple pr
evious overdoses (2.6). Average length of stay was 20.1 hours but 41%
of cases stayed less than 8 hours. Only one patient was readmitted wit
hin an 8-hour period. When discharged, 78% returned home. Unexpectedly
, 67% of patients were not referred to any therapeutic programme for d
rug addiction. Conclusion. This study shows the low mortality of AOO w
hen treated but also demonstrates the need to improve psychosocial eva
luation and referral of drug addicts admitted with AOO.