In this rejoinder to the three preceding comments, I provide some addi
tional philosophical warrant for the biomedical sciences' focus on mod
el organisms. I then relate the inquiries on model systems to the conc
ept of 'deep homology', and indicate that the issues that appear to di
vide my commentators and myself are in part empirical ones. I cite rec
ent work on model organisms, and especially C. elegans that supports m
y views. Finally, I briefly readdress some of the issues raised by Dev
elopmental Systems Theory.