ORPHANIN FQ STIMULATES PROLACTIN AND GROWTH-HORMONE RELEASE IN MALE AND FEMALE RATS

Authors
BRYANT W JANIK J BAUMANN M CALLAHAN P
Citation
W. Bryant et al., ORPHANIN FQ STIMULATES PROLACTIN AND GROWTH-HORMONE RELEASE IN MALE AND FEMALE RATS, Brain research, 807(1-2), 1998, pp. 228-233
Citations number
26
Categorie Soggetti
Neurosciences
Journal title
Brain research → ACNP
ISSN journal
00068993
Volume
807
Issue
1-2
Year of publication
1998
Pages
228 - 233
Database
ISI
SICI code
0006-8993(1998)807:1-2<228:OFSPAG>2.0.ZU;2-X
Abstract
Intracerebroventricular administration of Orphanin FQ (5.5, 55 or 550 pmol) caused a dose-related increase in prolactin secretion in both ma le and female rats and stimulated GK secretion in males. The magnitude of the prolactin secretory response was greater in females than in ma les. These effects of OFQ on prolactin and growth hormone release are the same as the stimulatory effects of the endogenous opioid peptides. (C) 1998 Elsevier Science B.V. All rights reserved.