HYPERPROLACTINEMIA - AN INDUCTOR OF NEOPLASTIC CHANGES IN ENDOMETRIUM- A REPORT OF 2 CASES

Authors
Citation
S. Dexeus et Pn. Barri, HYPERPROLACTINEMIA - AN INDUCTOR OF NEOPLASTIC CHANGES IN ENDOMETRIUM- A REPORT OF 2 CASES, Gynecological endocrinology, 12(4), 1998, pp. 273-275
Citations number
10
Categorie Soggetti
Endocrynology & Metabolism","Obsetric & Gynecology
Journal title
ISSN journal
09513590
Volume
12
Issue
4
Year of publication
1998
Pages
273 - 275
Database
ISI
SICI code
0951-3590(1998)12:4<273:H-AION>2.0.ZU;2-I
Abstract
Estrogen-dependent endometrial carcinomas habitually arise through a p recursor lesion such as endometrial hyperplasia. The hormonal environm ent of these patients remains unclear. Two cases of neoplastic changes in the endometrium of patients with a chronic hyperprolactinemia are presented. Despite the treatment with bromocriptine both patients deve loped endometrial adenocarcinomas. Possible mechanisms involved in the pathogenesis of these tumors are discussed.