Jr. Hoffman et al., SELECTIVE CERVICAL-SPINE RADIOGRAPHY IN BLUNT TRAUMA - METHODOLOGY OFTHE NATIONAL EMERGENCY X-RADIOGRAPHY UTILIZATION STUDY (NEXUS), Annals of emergency medicine, 32(4), 1998, pp. 461-469
Fear of failure to identify cervical spine injury has led to extremely
liberal use of radiography in patients with blunt trauma and remotely
possible neck injury. A number of previous retrospective and small pr
ospective studies have tried to address the question of whether any cl
inical criteria can identify patients, from among this group, at suffi
ciently low risk that cervical spine radiography is unnecessary. The N
ational Emergency X-Radiography Utilization Study (NEXUS) is a very la
rge, federally supported, multicenter, prospective study designed to d
efine the sensitivity, for detecting significant cervical spine injury
, of criteria previously shown to have high negative predictive value.
Done at 23 different emergency departments across the United States a
nd projected to enroll more than 20 times as many patients with cervic
al spine injury than any previous study, NEXUS should be able to answe
r definitively questions about the validity and reliability of clinica
l criteria used as a preliminary screen for cervical spine injury.