SYNTHESIS OF BENZOYL AND DODECANOYL DERIVATIVES FROM PROTECTED CARBOHYDRATES UNDER FOCUSED MICROWAVE IRRADIATION

Authors
LIMOUSIN C CLEOPHAX J LOUPY A PETIT A
Citation
C. Limousin et al., SYNTHESIS OF BENZOYL AND DODECANOYL DERIVATIVES FROM PROTECTED CARBOHYDRATES UNDER FOCUSED MICROWAVE IRRADIATION, Tetrahedron, 54(44), 1998, pp. 13567-13578
Citations number
56
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
44
Year of publication
1998
Pages
13567 - 13578
Database
ISI
SICI code
0040-4020(1998)54:44<13567:SOBADD>2.0.ZU;2-U
Abstract
A microwave assisted phase transfer catalyzed transesterification in b asic medium with methyl benzoate was studied for several carbohydrates . Small amounts of DMF were necessary to provide good yields (96-76%) within 15 minutes. This method was extended to the synthesis of dodeca noyl derivatives with 63-100% global yields within 15 to 30 minutes. R ate enhancements when compared to conventional heating in the same con ditions and specific microwave activation were mostly evidenced when f atty compounds (less reactive) were involved. (C) 1998 Elsevier Scienc e Ltd. All rights reserved.