SOME MECHANISMS OF INTERACTION BETWEEN PE STICIDES AND LIPID BILAYERSOF LIVING CELLS MEMBRANES

Authors
Citation
Vn. Golubev, SOME MECHANISMS OF INTERACTION BETWEEN PE STICIDES AND LIPID BILAYERSOF LIVING CELLS MEMBRANES, Uspehi himii, 62(7), 1993, pp. 726-734
Citations number
107
Categorie Soggetti
Chemistry
Journal title
ISSN journal
00421308
Volume
62
Issue
7
Year of publication
1993
Pages
726 - 734
Database
ISI
SICI code
0042-1308(1993)62:7<726:SMOIBP>2.0.ZU;2-O
Abstract
Some mechanisms of interaction of pesticide molecules of different che mical structure with bilayer lipid membranes (BLM) of living cells hav e been exposed. It has been shown that depending on the hydrophobic ra dical length, the dipole moment of the hydrophilic group, and other pa rameters characterising pesticide molecule, its interaction with BLM i s realised according to one of the three main mechanisms: by the solub ilization of the pesticide molecules inside the hydrocarbon region of BLM, by the adsorption of these molecules to the region of the localis ation of hydrophilic heads of membrane phospholipides, or by the incor poration of amphiphile pesticide molecules in the intermediate region of BLM.