MACROCYCLIZATION OF TERMINAL BIS-ALLYLIC CHLORIDES VIA AN INTRAMOLECULAR GEM-DIALKYLATION OF MALONONITRILE OR METHYL CYANOACETATE

Authors
CHANTIGNY Y TORO A LEMELIN CA DESLONGCHAMPS P
Citation
Y. Chantigny et al., MACROCYCLIZATION OF TERMINAL BIS-ALLYLIC CHLORIDES VIA AN INTRAMOLECULAR GEM-DIALKYLATION OF MALONONITRILE OR METHYL CYANOACETATE, Tetrahedron letters, 39(43), 1998, pp. 7839-7840
Citations number
4
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
43
Year of publication
1998
Pages
7839 - 7840
Database
ISI
SICI code
0040-4039(1998)39:43<7839:MOTBCV>2.0.ZU;2-#
Abstract
A procedure is described for the stereospecific synthesis of 13-member ed trienic macrocycles from suitable acyclic bis-allylic chlorides via an intramolecular gem-dialkylation of malononitrile or methyl cyanoac etate. (C) 1998 Elsevier Science Ltd. All rights reserved.