COMPLEX CAGED POLYISOPRENYLATED BENZOPHENONE DERIVATIVES, SAMPSONIONE-A AND SAMPSONIONE-B, FROM HYPERICUM-SAMPSONII

Authors
HU LH SIM KY
Citation
Lh. Hu et Ky. Sim, COMPLEX CAGED POLYISOPRENYLATED BENZOPHENONE DERIVATIVES, SAMPSONIONE-A AND SAMPSONIONE-B, FROM HYPERICUM-SAMPSONII, Tetrahedron letters, 39(43), 1998, pp. 7999-8002
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
43
Year of publication
1998
Pages
7999 - 8002
Database
ISI
SICI code
0040-4039(1998)39:43<7999:CCPBDS>2.0.ZU;2-1
Abstract
The aerial parts of the Chinese medicinal plant Hypericum sampsonii yi elded two novel metabolites, sampsoniones A and B, which are character ised by their unique tetracyclo-polyketonic core with benzoyl, 3-methy l-2-butenyl and geranyl substituents. Their structures were determined by detailed spectral analysis. Sampsonione A exhibited moderate cytot oxicity to P388 cancer cell line. (C) 1998 Elsevier Science Ltd. All r ights reserved.