PANCREATIC-POLYPEPTIDE STIMULATES CORTICOSTERONE SECRETION BY ISOLATED RAT ADRENOCORTICAL-CELLS

Authors
ANDREIS PG TORTORELLA C NUSSDORFER GG
Citation
Pg. Andreis et al., PANCREATIC-POLYPEPTIDE STIMULATES CORTICOSTERONE SECRETION BY ISOLATED RAT ADRENOCORTICAL-CELLS, Life sciences, 53(17), 1993, pp. 1353-1356
Citations number
14
Categorie Soggetti
Biology,"Medicine, Research & Experimental
Journal title
Life sciences → ACNP
ISSN journal
00243205
Volume
53
Issue
17
Year of publication
1993
Pages
1353 - 1356
Database
ISI
SICI code
0024-3205(1993)53:17<1353:PSCSBI>2.0.ZU;2-N
Abstract
Pancreatic polypeptide (PP) dose-dependently enhanced both basal and s ubmaximally ACTH-stimulated corticosterone production by dispersed zon a fasciculata/reticularis cells of the rat adrenal gland. Conversely P P did not affect either basal or ACTH- and angiotensin-II-stimulated a ldosterone and corticosterone secretion of zona glomerulosa cells. The se findings could throw light on the physiological significance of the marked increase in the pancreatic release of PP during stresses.