THE INHIBITION OF HUMAN NEURONAL K+ CURRENTS BY GENERAL ANESTHETIC AGENTS IS ALTERED BY EXTRACELLULAR K+

Authors
FRIEDERICH P URBAN BW
Citation
P. Friederich et Bw. Urban, THE INHIBITION OF HUMAN NEURONAL K+ CURRENTS BY GENERAL ANESTHETIC AGENTS IS ALTERED BY EXTRACELLULAR K+, Molecular brain research, 60(2), 1998, pp. 301-304
Citations number
18
Categorie Soggetti
Neurosciences
Journal title
Molecular brain research → ACNP
ISSN journal
0169328X
Volume
60
Issue
2
Year of publication
1998
Pages
301 - 304
Database
ISI
SICI code
0169-328X(1998)60:2<301:TIOHNK>2.0.ZU;2-5
Abstract
We demonstrate for the first time that the extracellular potassium con centration influences the inhibition of human neuronal delayed rectifi er potassium currents by general anesthetics. This observation suggest s a modulatory role for extracellular potassium ions in the action of some general anesthetic agents. (C) 1998 Elsevier Science B.V. All rig hts reserved.