P. Friederich et Bw. Urban, THE INHIBITION OF HUMAN NEURONAL K+ CURRENTS BY GENERAL ANESTHETIC AGENTS IS ALTERED BY EXTRACELLULAR K+, Molecular brain research, 60(2), 1998, pp. 301-304
We demonstrate for the first time that the extracellular potassium con
centration influences the inhibition of human neuronal delayed rectifi
er potassium currents by general anesthetics. This observation suggest
s a modulatory role for extracellular potassium ions in the action of
some general anesthetic agents. (C) 1998 Elsevier Science B.V. All rig
hts reserved.