As in other aquatic organisms, disease can have a serious impact upon
blue crab populations. Various infectious agents, including viruses, b
acteria, fungi, protozoans, and metazoans have been documented in blue
crabs. In many cases, large scale morbidity or mortality has been obs
erved. Nonetheless, our knowledge of disease impacts, as well as means
for managing these problems, is rudimentary. Much information is need
ed to define quantitatively the importance of various diseases. Becaus
e of the exclusive reliance of blue crab shedding operations upon wild
stocks, there is a close interrelationship between the health of crab
s in the natural environment and those maintained in shedding operatio
ns. This also points out the dependence of this growing industry upon
healthy wild populations for continued success. The purpose of this pa
per is to provide a review of the current literature on important dise
ases of blue crabs, with special emphasis on shell disease, a stress-r
elated syndrome that may provide useful insights into assessing stress
in blue crab populations. These studies indicate that further researc
h is needed in assessing stress in blue crab populations, so that risk
factors (e.g., water quality deterioration) that lead to compromised
health are defined, and more effective management strategies can be de
veloped.