INDICATORS OF HYPOXIA IN CEREBROSPINAL-FLUID OF HYDROCEPHALIC CHILDREN WITH SUSPECTED SHUNT MALFUNCTION

Authors
CASTROGAGO M RODRIGUEZSEGADE S CAMINA F BOLLAR A RODRIGUEZNUNEZ A
Citation
M. Castrogago et al., INDICATORS OF HYPOXIA IN CEREBROSPINAL-FLUID OF HYDROCEPHALIC CHILDREN WITH SUSPECTED SHUNT MALFUNCTION, Child's nervous system, 9(5), 1993, pp. 275-277
Citations number
27
Categorie Soggetti
Neurosciences,Pediatrics
Journal title
Child's nervous system → ACNP
ISSN journal
02567040
Volume
9
Issue
5
Year of publication
1993
Pages
275 - 277
Database
ISI
SICI code
0256-7040(1993)9:5<275:IOHICO>2.0.ZU;2-0
Abstract
We used high performance liquid chromatography to determine the concen tration of purine metabolites in the cerebrospinal fluid of three hydr ocephalic children with a history of shunt malfunction. Hypoxanthine a nd xanthine levels were high in comparison with controls. We consider these purines to be valuable indicators of disturbance of neuronal met abolism following the sustained rise in intracranial pressure caused b y shunt valve malfunction.