N. Kumar et al., CHARACTERIZATION OF TUBULAR ADENOMA OF BREAST - DIAGNOSTIC PROBLEM INFINE-NEEDLE ASPIRATES (FNAS), Cytopathology, 9(5), 1998, pp. 301-307
FNA smears from six histologically documented cases of tubular adenoma
of breast were critically analysed and compared with 10 histologicall
y confirmed cases of fibroadenoma (five pericanalicular and five intra
canalicular). Initially a cytological diagnosis of tubular adenoma was
rendered only in one case. On review, two cases could be characterize
d as tubular adenoma, while the findings were suggestive in two others
. The features helpful in diagnosis of tubular adenoma were the presen
ce of benign ductal cells as three-dimensional cohesive balls and tubu
lar structures in highly cellular smears. Stroma was conspicuously sca
nty or absent. Myoepithelial cells were present along with sheets of d
uctal cells as well as bipolar naked nuclei. Confusion with fibroadeno
ma occurred in two cases due to presence of a stag-horn pattern of duc
tal cells.