M. Schubert et al., AMPHIOXUS AMPHIDRAL ENCODING A LIM-DOMAIN PROTEIN - EXPRESSION IN THEEPIDERMIS BUT NOT IN THE PRESUMPTIVE NEUROECTODERM, Mechanisms of development, 76(1-2), 1998, pp. 203-205
The sequence and developmental expression have been determined for amp
hioxus AmphiDRAL, which encodes a homolog of vertebrate DRAL (down-reg
ulated in rhabdomyosarcoma LIM-protein). This is the first clear examp
le of a DRAL homolog in an invertebrate. Detectable developmental expr
ession begins at the gastrula stage in the epidermis, but not in the n
euroectoderm; thus the early stages of AmphiDRAL expression indicate t
he neural/non-neural boundary. During subsequent embryonic stages, exp
ression continues in the epidermis (but not in the developing central
nervous system) until it fades during the later larval stages. (C) 199
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