K. Hartung et al., SINGLE-READ SEQUENCE TAGS OF A LIMITED NUMBER OF GENOMIC DNA FRAGMENTS PROVIDE AN INEXPENSIVE TOOL FOR COMPARATIVE GENOME ANALYSIS, Yeast (Chichester), 14(14), 1998, pp. 1327-1332
Single-read sequences from both ends of 415 3-kb average size genomic
DNA fragments of Candida albicans were compared with the complete sequ
ence data of Saccharomyces cerevisiae. Comparison at the protein level
, translated DNA against protein sequences, revealed 138 sequence tags
with clear similarity to S. cerevisiae proteins or open reading frame
s. One case of synteny was found for the open reading frames of RAD16
and LYS2, which are adjacent to each other in S. cerevisiae and C. alb
icans. (C) 1998 John Wiley & Sons, Ltd.