GENETIC-MAPPING OF MOUSE CENTROMERE PROTEIN (INCENP AND CENPE) GENES

Authors
FOWLER KJ SAFFERY R KILE BT IRVINE DV HUDSON DF TROWELL HE CHOO KHA
Citation
Kj. Fowler et al., GENETIC-MAPPING OF MOUSE CENTROMERE PROTEIN (INCENP AND CENPE) GENES, Cytogenetics and cell genetics, 82(1-2), 1998, pp. 67-70
Citations number
21
Categorie Soggetti
Cell Biology","Genetics & Heredity
Journal title
Cytogenetics and cell genetics → ACNP
ISSN journal
03010171
Volume
82
Issue
1-2
Year of publication
1998
Pages
67 - 70
Database
ISI
SICI code
0301-0171(1998)82:1-2<67:GOMCP(>2.0.ZU;2-6
Abstract
Inner centromere protein (INCENP) and centromere protein E (CENPE) are two functionally important proteins of the higher eukaryotic centrome re. Using a mouse Incenp genomic DNA and a mouse Cenpe cDNA to analyze recombinant inbred mouse sets, as well as interspecific backcross pan els, we have mapped these genes to the proximal regions of mouse Chrom osomes 19 and 6, respectively. Comparison of Cenpe and human CENPE, wh ich maps to chromosome region 4q24-->q25, has further identified a new region of homology between the two species.