Hc. Ardley et al., FINE MAPPING OF 12 PREVIOUSLY UNASSIGNED EST CLONES TO INDIVIDUAL YACS IN THE FAMILIAL ALZHEIMERS-DISEASE (FAD) REGION OF CHROMOSOME 14Q24.3, Cytogenetics and cell genetics, 82(1-2), 1998, pp. 107-109
We have constructed an approximately 4-Mb YAC contig spanning the micr
osatellite markers D14S1028-D14S61 on chromosome 14q24.3 using oligonu
cleotide primers to microsatellite markers, ESTs and the genes PSEN1,
FOS, TGFB3 and UBE2L1. This contig consists of 44 ICI YACs and 5 megaC
EPH YACs. The data reported here should aid the final construction of
an integrated map of chromosome 14 and allow the identification and ac
curate mapping of additional novel ESTs within this region.