INCREASED LIPOPROTEIN (A) AS AN INDEPENDENT RISK FACTOR FOR CARDIOVASCULAR AND CEREBROVASCULAR DISEASES

We quantified serum lipoprotein(a) [Lp(a)] in 1266 healthy persons and established the reference value of Lp(a) in groups of age and sex. Th e Lp(a) in myocardial infarction (MI) survivors, stroke and primary hy pertension patients were determined in comparison with that of age-mat ched normal controls. Moreover, cholesterol, triglyceride, HDL-cholest erol, apo Al and apo B were measured. The Lp(a) concentrations were no t correlated with other lipids in normal controls and patients. Our re sults suggest that increased Lp(a) is an independent risk factor for M I and stroke patients. The total detective rate of abnormal lipids in MI and stroke patients was as high as 50% and 53.8% (Lp(a) excluded) a s well as 65.7% and 64.9% (Lp(a) included) respectively.