NASAL SCLEROMA (RHINOSCLEROMA) - PATHOLOGICAL AND CLINICAL-RESULTS

Histologic, immunohistochemical and ultrastructural results of a rhino scleroma diagnosed bioptically on a 38 aged man are demonstrated. The characteristic light microscopic sign is a plasmocytic inflammatory in filtrate with dense packed foamy transformed macrophages (Mikulicz cel ls) ultrastructurally containing diplobacilli (Klebsiella rhinosclerom atis, gram negative agent of the lesion). The lesion has to be differe ntiated as of other inflammatory diseases as of plasmocytoma. A local application of acriflavin solution 2% was of therapeutical benefit.