COLUMNS AND PACKING METHODS

A lot of research has been done to develop methods which allowed to re producibly fill analytical columns. Nowadays, it's no longer a problem to pack efficient columns with a broad variety of packing materials a nd particle sizes. However, from a technical point of view, it's not s o easy to fill larger diameter columns using the same technology. Ther efore, alternative methods had to be developed. In this contribution a n over-view is given of the most important technologies which are nowa days commercially available to pack preparative columns for laboratory and production scale purposes.