BIO-OSS(R) - A RESORBABLE BONE SUBSTITUTE

BIO-OSS is an allergen-free bone substitute material of bovine origin, used to fill bone defects or to reconstruct ridge configurations. Sev enty one patients (39 female, 32 male) received 126 BIO-OSS implantati ons. Some health parameters or habits were documented to eliminate pos sible risk factors of influence. The diameter of jaw defects filled wi th BIO-OSS was measured. There was a significant influence of the defe ct size on the healing result. In X-ray controls, BIO-OSS served to id entify the surrounding native bone. The density of the BIO-OSS areas w as higher than in control sites. These radiological results were suppo rted by bone biopsies. Histologically, the permanency of the BIO-OSS w as still recognizable after 6 years and longer. The ingrowth of newly formed bone in the BIO-OSS scaffold explained the increased density of the implanted regions. There were no clinical signs of BIO-OSS resorp tion. Therefore, we can assume that form corrections achieved by BIO-O SS insertions will last.