A survey was undertaken of senior medical specialists in drug dependen
ce in England and Wales, enquiring about their attitudes and practices
concerning the prescription of amphetamines to dependent users. Of th
e 149 who replied, 60% saw a role for amphetamine prescribing, with 46
% currently doing so. Of those who did not prescribe, 32% would Like t
o have done so. Respondents often did not know if general practitioner
s in their area were prescribing amphetamines. Many could not estimate
the percentage of injecting amphetamine users in their area. There wa
s a wide range in the dosage of amphetamine prescribed with a mean max
imum of 66 mg, There was agreement about entry criteria for prescribin
g programmes and also on ways of monitoring those receiving amphetamin
e, Our results indicate that amphetamine prescribing is widespread in
England and Wales although there is little scientific evidence for its
efficacy. We have developed some guidelines for good practice, drawin
g on our own and others' experience.