STRUCTURAL ANALOGS OF CUMAMBRIN-B FROM THE FLOWER OF CHRYSANTHEMUM-BOREALE

Authors
JANG DS YANG MS HA TJ PARK KH
Citation
Ds. Jang et al., STRUCTURAL ANALOGS OF CUMAMBRIN-B FROM THE FLOWER OF CHRYSANTHEMUM-BOREALE, Archives of pharmacal research, 21(5), 1998, pp. 591-594
Citations number
12
Categorie Soggetti
Pharmacology & Pharmacy","Chemistry Medicinal",Biology
Journal title
Archives of pharmacal research → ACNP
ISSN journal
02536269
Volume
21
Issue
5
Year of publication
1998
Pages
591 - 594
Database
ISI
SICI code
0253-6269(1998)21:5<591:SAOCFT>2.0.ZU;2-5
Abstract
The structural analogues of cumambrin B (1, 2, 3, 4) were isolated fro m the flower of Chrysanthemum boreale Makino. The structures of compou nds were determined by two-dimensional H-1-H-1 COSY and C-13-H-1 COSY spectra with the aid of homonuclear and heteronuclear double resonance experiment. The stereochemistry of compounds has been verified from s ingle crystal X-ray diffraction oi cumambrin A (2). The antimicrobial activities of these guaianolides have been studied.