LATTICE REPRESENTATIONS OF GLOBULAR-PROTEINS - HOW GOOD ARE THEY

Using a number of different lattice models of proteins, the problems i ntroduced by the discretization of a protein backbone are discussed an d examples of the most typical errors arising in low coordination numb er lattices presented. The geometric properties of different lattices used in the literature are compiled, and for all of them the resulting alpha-carbon models of proteins are described in detail and compared to the original structures obtained from experiment. (C) 1993 by John Wiley & Sons, Inc.