In a case-control study of 1,004 lung cancer cases and 1,004 populatio
n controls, all nonsmokers (71 cases, 236 controls) were interviewed f
or their exposure to environmental tobacco smoke. On the basis of indi
ces of duration, we separated intermediate and high exposures from low
or no exposure. The odds ratio for high exposure was 2.09 (95% confid
ence interval = 1.02-4.28). Exposure from the spouse was only weakly a
ssociated with lung cancer risk. We found little association for expos
ure during childhood. High exposure at the work place showed an odds r
atio of 1.91. There was little indication of confounding by dietary ha
bits.