Jf. Muir et A. Cuvelier, MANAGEMENT OF CHRONIC RESPIRATORY-FAILURE - INTEREST OF LONG-TERM RESPIRATORY ASSISTANCE AT HOME, Bulletin de l'Academie nationale de medecine, 182(6), 1998, pp. 1139-1158
Chronic respiratory failure represents an important problem of public
health if we consider the potential high number of patients needing to
be treated and the expenses linked to a complex treatment having to b
e applied at home, Progress of knowledge about chronic respiratory fai
lure conducted in the early' 80 to the publication of the BMRC and NOT
T studies where long-term oxygentherapy was demonstrated to be efficie
nt in severe hypoxic patients with chronic obstructive pulmonary disea
se, reducing need for hospitalisation for acute respiratory failure an
d thus improving quality of life. In the early '80, several retrospect
ive studies showed the interest of mechanical ventilation in the manag
ement of chronic respiratory failure secondary to restrictive defects
mainly due to chest wall deformities, neuromuscular diseases and tuber
culous sequelae. Tracheostomy was initially used as a connection mode
to the respirator, the technological progress obtained with the treatm
ent of sleep apnea syndrome with nasal continuous positive airway pres
sure made convenient masks available, which were in turn used with suc
cess to Ventilate ''non invasively'' patients with restrictive defects
at horne as well as in acute respiratory failure Nowadays, chronic re
spiratory failure is largely managed at home with the help of respirat
ory assistance organizations which manage in France through the public
ANTADIR network more than 50 000 patients.