BIOSYNTHESIS OF ISOPRENOIDS IN ESCHERICHIA-COLI - RETENTION OF THE METHYL H-ATOMS OF 1-DEOXY-D-XYLULOSE

Authors
GINER JL JAUN B
Citation
Jl. Giner et B. Jaun, BIOSYNTHESIS OF ISOPRENOIDS IN ESCHERICHIA-COLI - RETENTION OF THE METHYL H-ATOMS OF 1-DEOXY-D-XYLULOSE, Tetrahedron letters, 39(44), 1998, pp. 8021-8022
Citations number
9
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
44
Year of publication
1998
Pages
8021 - 8022
Database
ISI
SICI code
0040-4039(1998)39:44<8021:BOIIE->2.0.ZU;2-X
Abstract
Investigation of isoprenoid biosynthesis in E. coli using [1,1,1-H-2(3 )]-1-deoxy-D-xylulose shows the methyl group of 1-deoxyxylulose to be incorporated into the methyl groups of ubiquinone originating from the methyl group of IPP and the (Z)-methyl group of DMAPP, and that this incorporation involves nd loss of methyl hydrogen atoms. (C) 1998 Else vier Science Ltd. All rights reserved.