A SHORT SYNTHESIS OF THE MARINE BIOACTIVE METABOLITE (+ -) GIROLLINE/

Authors
MARCHAIS S ALMOURABIT A AHOND A POUPAT C POTIER P
Citation
S. Marchais et al., A SHORT SYNTHESIS OF THE MARINE BIOACTIVE METABOLITE (+ -) GIROLLINE/, Tetrahedron letters, 39(44), 1998, pp. 8085-8088
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
44
Year of publication
1998
Pages
8085 - 8088
Database
ISI
SICI code
0040-4039(1998)39:44<8085:ASSOTM>2.0.ZU;2-#
Abstract
A new 2 step synthesis of (+/-) girolline 1 starting from the easily a vailable alpha-chloro-beta-aminoaldehyde 4 and 2-aminoimidazole 5 is d escribed. The reaction of 4 with 5, followed by deprotection, affords the three diastereoisomer. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.