NEW THERAPEUTIC APPROACHES TO REVERSING INSULIN-RESISTANCE

Authors
SONNENBERG GE KOTCHEN TA
Citation
Ge. Sonnenberg et Ta. Kotchen, NEW THERAPEUTIC APPROACHES TO REVERSING INSULIN-RESISTANCE, Current opinion in nephrology and hypertension, 7(5), 1998, pp. 551-555
Citations number
51
Categorie Soggetti
Urology & Nephrology","Peripheal Vascular Diseas
Journal title
Current opinion in nephrology and hypertension → ACNP
ISSN journal
10624821
Volume
7
Issue
5
Year of publication
1998
Pages
551 - 555
Database
ISI
SICI code
1062-4821(1998)7:5<551:NTATRI>2.0.ZU;2-D
Abstract
Insulin resistance may be associated with hypertension and additional cardiovascular disease risk factors. Troglitazone, a thiazolidinedione , is an insulin sensitizing agent that has recently been approved by t he USA Food and Drug Administration for the treatment of type II diabe tes. Thiazolidinediones and other agents that increase insulin sensiti vity, and lipid lowering drugs attenuate the development of hypertensi on in animal models and in limited clinical studies. Curr Coin Nephrol Hypertens 7:551-555. (C) 1998 Lippincott Williams & Wilkins.