Objective: To increase the awareness of bovine serum albumin (BSA) sen
sitivity as a potentially lethal complication during ET. Design: Case
report. Setting: Routine ET in university hospital. Patient(s): A 26-y
ear-old woman who was undergoing her first ET. Intervention(s): ET wit
h BSA containing standard fluid medium. Main Outcome Measure(s): Speci
fic immunoglobulin (Ig) E antibodies and skin tests. Result(s): The pa
tient demonstrated increased levels of specific IgB antibodies to BSA
and a clearly positive scratch test for BSA. Conclusion(s): Anaphylact
ic reactions to BSA can occur during ET. The risk can be reduced subst
antially if a detailed medical history is obtained. (Fertil Steril(R)
1998;70:771-3. (C) 1998 by American Society for Reproductive Medicine.
).