The past 10 years have seen the discovery of unexpected Levels of cons
ervation of gene content and gene orders over millions of years of evo
lution within grasses, crucifers, Legumes, some trees, and Solanaceae
crops, Within the grasses, which include the three 500-million-ton-plu
s-per-year crops (wheat, maize, and rice), and the crucifers, which in
clude all the Brassica crops, colinearity Looks good enough to do most
map-based cloning only in the small genome model species, rice and Ar
abidopsis. Elsewhere, knowledge gained in a few major crops is being p
ooled and applied across the board. The extrapolation of information f
rom the well-studied species to orphan crops, which include many tropi
cal species, is providing a solid base for their improvement. Genome r
earrangements are giving new insights into evolution. In fact, compara
tive genetics is the key that will unlock the secrets of crop plants w
ith genomes Larger than that of humans.