ADVANCED TESTICULAR GERM-CELL TUMOR IN A HEMOPHILIC PATIENT WITH HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION

A stage IIIB anaplastic seminoma which occurred in an HIV-infected hem ophilia is reported. The patient with hemophilia A was 36 years old an d had been seropositive for HIV antibody for 3 years. Inguinal orchiec tomy and subsequent chemoradiotherapy for retoroperitoneal lymphadenop athy were performed and a marker negative partial response was obtaine d. in spite of a low initial CD4+ lymphocyte count (90/mu l), the pati ent tolerated the treatment well without life-threatening opportunisti c infection. Although factor VIII supplement was performed, continuous bleeding from the operative wound made postoperative care difficult.