In 1997, more than 40 new medicinal chemical entities in the field of
anti-infectives were presented during the 37th Interscience Conference
on Antimicrobial Agents and Chemotherapy, held in Toronto. Among thes
e novelties, three compounds could or will be candidates for clinical
development: HMR 3647, a ketolide derivative; T-3811, a new quinolone;
and GM 237,354, a new antifungal compound. Other molecules are potent
ial lead compounds.