THE SYSTEMATIC DEFINITION OF ORGANIC-REACTIONS

A logical system is presented to describe organic reactions. It is bas ed on the net structural change in a reaction, rather than on substruc ture searching. This system rigorously provides a place for any reacti on. It is very simple to use by hand, but, since it is also numerical, it provides a basis for organizing and retrieving reactions in a data base by computer. The effectiveness of a program, COGNOS, written to i mplement and test the system on a large database, lends confidence in this logic for organizing reactions.