Introduction. Medicine for Humanity is a multidisciplinary team of hea
lth care professionals, travelling to developing areas throughout the
world on medical missions. The following is one of many technically ch
allenging and unique cases presented for treatment. Case. A 38-year-ol
d woman gradually developed a giant mass arising from the right labium
majus, extending into the retroperitoneum, Surgical resection was per
formed by abdominal and perineal teams. Intraoperative blood loss was
approximately 10,000 mi, requiring 18 units of whole blood transfusion
-including 6 units acutely donated by members of the surgical team. A
''pack and go back'' technique was used for hemostasis. The tumor weig
hed 19.8 kg, Final histology confirmed an aggressive angiomyxoma, Conc
lusion. This patient had the largest, histologically confirmed, aggres
sive angiomyxoma described to date. The surgical management of this ca
se followed the principles in treating hemorrhagic shock, but required
modifications based on availability of resources in Cebu City, Philip
pines. (C) 1998 Academic Press.