Major progress in sequencing the genome of Sulfolobus solfataricus has
been closely concerted with the characterization and sequencing of ma
ny extrachromosomal genetic elements, including viruses, cryptic plasm
ids and conjugative plasmids, as well as mobile archaeal introns and t
ransposons. The rafter have provided a basis for developing the first
generation of vectors that are now being used to study the genetics of
Sulfolobus and other Archaea.