T. Lehnert et al., SURGERY FOR LOCAL RECURRENCE OR DISTANT METASTASES IN PATIENTS AGED 75 YEARS OR OLDER, European journal of surgical oncology, 24(5), 1998, pp. 418-422
Between 1982 and 1997, a total of 105 patients aged 75 years or older
(median age 78 years) under,vent surgical treatment for recurrent soli
d tumours, The most frequent primary tumours mere melanoma, colorectal
carcinoma and breast cancer. Sixty-one patients had complete removal
of recurrent tumour. Post-operative mortality was 3.8% (four of 105 pa
tients). The median hospital stay was 16 days and the post-operative h
ospital stay was 10 days. At a median follow-up of 57 months, 77 patie
nts had died. Twenty one patients died of causes unrelated to the tumo
ur. The overall survival of 105 patients was 35% at 3 years and 27% at
5 years. Following R0 resection, 5-year survival was 43% (n = 61) and
in the absence of post-operative complications even reached 50% (n=47
). Survival correlated with completeness of tumour resection (P<0.0001
) and post-operative complications (P=0.021). No significant correlati
on could be established between survival and age, ASA score, blood rep
lacement, primary tumour location or sex. Elderly patients presenting
with recurrent tumour should be evaluated for surgical resection, If t
umour removal is complete and post-operative complications are avoided
, a 5-year survival rate of over 40% may be expected.