A SHORT AND FACILE SYNTHETIC ROUTE TO PRENYLATED FLAVONES - CYCLODEHYDROGENATION OF PRENYLATED 2'-HYDROXYCHALCONES BY A HYPERVALENT IODINE REAGENT

Authors
GULACSI K LITKEI G ANTUS S GUNDA TE
Citation
K. Gulacsi et al., A SHORT AND FACILE SYNTHETIC ROUTE TO PRENYLATED FLAVONES - CYCLODEHYDROGENATION OF PRENYLATED 2'-HYDROXYCHALCONES BY A HYPERVALENT IODINE REAGENT, Tetrahedron, 54(45), 1998, pp. 13867-13876
Citations number
29
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
45
Year of publication
1998
Pages
13867 - 13876
Database
ISI
SICI code
0040-4020(1998)54:45<13867:ASAFSR>2.0.ZU;2-Z
Abstract
The first synthesis of the prenylated flavones kanzonol-D (1), -E (3) and yinyanghuo-C (4) was accomplished by cyclodehydrogenation of the a ppropriately substituted 2'-hydroxychalcones 16, 14 and 11, respective ly, in presence of phenyl-iodine(III) diacetate (PIDA) / potassium hyd roxide in methanol. The synthesis of kanzonol-B (13) was also achieved from the 2'-hydroxychalcone 12. (C) 1998 Elsevier Science Ltd. All ri ghts reserved.