Background Operations for large and recurrent abdominal hernias have a
high associated recurrence rate, although it is lower when prosthetic
material is used. Expanded polytetrafluoroethylene (ePTFE) seems to b
e the best tolerated prosthetic material in surgery. Methods A series
of 45 ventral hernias repaired using ePTFE for closure or reinforcemen
t of the herniorrhaphy has been evaluated prospectively. Thirty-six we
re midline incisional hernias and nine were transverse or pararectal v
entral hernias. There were 13 recurrent ventral hernias and three defe
cts were operated as an emergency procedure. The patch was sutured to
the anterior aponeurosis with a running non-absorbable suture. Some ot
her kind of intra-abdominal procedure was undertaken in 12 cases. Resu
lts ePTFE was well tolerated. Complications occurred in five patients.
Major complications were found in three patients: cutaneous:necrosis
requiring a myocutaneous flap; and infection of the prosthesis (primar
y, and secondary to enterocutaneous fistula due to diverticulitis, bot
h requiring removal of the patch). Mean follow-up was 39 months and he
rnia recurrence occurred in only one patient. Conclusion This clinical
experience shows that ePTFE is a very reliable prosthetic material fo
r the repair of abdominal wall hernias.