Certain regions and places in the United States seem more prone to exp
erience population loss. This study examines the geography of this ''e
mptying'' process based on 1990-1995 census data and presents maps whi
ch show county-level patterns of population change and several related
components. The major emptying areas are the Great Plains, Western Co
rn Belt, Lower Mississippi Valley, Central Appalachia, and metropolita
n centers in the Northeast. Population change is correlated with socia
l and economic variables, characteristics shared by the 635 losing cou
nties are examined, and profiles of the major losing areas are present
ed. Net outmigration emerges as the dominant problem, together with th
e inability to find a substitute for declining employment in agricultu
re and mining, or in the case of older metropolitan areas, to develop
a new employment base.