QUANTITATIVE-ANALYSIS BY RENORMALIZED ENTROPY OF INVASIVE ELECTROENCEPHALOGRAPH RECORDINGS IN FOCAL EPILEPSY

Invasive electroencephalograph (EEG) recordings of ten patients suffer ing from focal epilepsy were analyzed using the method of renormalized entropy. Introduced as a complexity measure for the different regimes of a dynamical system, the feature was tested here for its spatiotemp oral behavior in epileptic seizures. In all patients a decrease of ren ormalized entropy within the ictal phase of seizure was found. further more, the strength of this decrease is monotonically related to the di stance of the recording location to the focus. The results suggest tha t the method of renormalized entropy is a useful procedure for clinica l applications like seizure detection and localization of epileptic fo ci. [S1063-651X(98)11710-5].