OBJECTIVE: To evaluate the fertility potential after primary cesarean
section (CS) in anovulatory patients treated for ovulation induction w
ith gonadotropins. STUDY DESIGN: A controlled, prospective study was c
onducted on 97 anovulatory patients who delivered a neonate either abd
ominally or vaginally after ovulation induction with human menopausal
gonadotropin/human chorionic gonadotropin (hMG/hCG). After four cycles
of hMG/hCG therapy, cumulative pregnancy rates and abortions were obs
erved. In both groups, patients who did not conceive underwent hystero
salpingography to evaluate uterine and tubal patency. RESULTS: The cum
ulative pregnancy rate in the anovulatory, post-cesarean section patie
nts treated with hMG/hCG was 61.9%, as compared to 59.6% in the contro
l group (statistically nonsignificant). The abortion rate was similar
in both groups. CONCLUSION: The risk of uterine or tubal infertility i
s probably not substantially increased in patients on whom uncomplicat
ed cesarean sections have been performed. Anovulatory patients who con
ceive after treatment with gonadotropins and deliver abdominally shoul
d be referred for medical treatment before evaluation of any uterine o
r tubal infertility.