EFFECT OF THE THIOALKYL CHAIN VARIATION IN THE EFFICIENCY OF SATE PRONUCLEOTIDES

Authors
EGRON D PERIGAUD C AUBERTIN AM IMBACH JL GOSSELIN C
Citation
D. Egron et al., EFFECT OF THE THIOALKYL CHAIN VARIATION IN THE EFFICIENCY OF SATE PRONUCLEOTIDES, Nucleosides & nucleotides, 17(9-11), 1998, pp. 1725-1729
Citations number
7
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
17
Issue
9-11
Year of publication
1998
Pages
1725 - 1729
Database
ISI
SICI code
0732-8311(1998)17:9-11<1725:EOTTCV>2.0.ZU;2-0
Abstract
The synthesis and the anti-HIV activity of two mononucleoside phosphot riester derivatives of 3'-azido-2',3''-dideoxythymidine (AZT) and 2',3 '-dideoxyadenosine (ddA) incorporating a new kind of phosphate protect ing group, namely S-pivaloyl-4-thiobutyl (tBuSATB), are reported.