PARALLEL-STRANDED DUPLEX DNA AND SELF-ASSEMBLED QUARTET STRUCTURES FORMED BY ISOGUANINE AND RELATED BASES

Authors
SEELA F WEI CF MELENEWSKI A FEILING E
Citation
F. Seela et al., PARALLEL-STRANDED DUPLEX DNA AND SELF-ASSEMBLED QUARTET STRUCTURES FORMED BY ISOGUANINE AND RELATED BASES, Nucleosides & nucleotides, 17(9-11), 1998, pp. 2045-2052
Citations number
18
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
17
Issue
9-11
Year of publication
1998
Pages
2045 - 2052
Database
ISI
SICI code
0732-8311(1998)17:9-11<2045:PDDASQ>2.0.ZU;2-I
Abstract
Parallel-stranded (ps) oligonucleotide duplexes are described containi ng isoguanine-cytosine and/or 5-methylisocytosine-guanine base pairs. A parallel hybrid is also formed when 5-aza-7-deazaguanine base pairs with guanine while the base pair with isoguanine results in an antipar allel duplex. Oligomers such as d(T(4)isoG(4)T(4)) form self-assembled tetraplexes which show a cation selectivity different from that of th e G-quartet.