Purpose: To characterize the clinical features of proliferative diabet
ic retinopathy (PDR) with asteroid hyalosis treated by pars plana vitr
ectomy. Methods: Vitrectomy was performed in 26 eyes with PDR accompan
ied by asteroid hyalosis (7 eyes with vitreous hemorrhage, 6 eyes with
tractional retinal detachment with vitreous hemorrhage, and 13 eyes w
ith tractional retinal detachment without vitreous hemorrhage). We obs
erved the occurrence of posterior vitreous detachment intraoperatively
and evaluated the clinical characteristics retrospectively. Results:
in 24 eyes, posterior vitreous detachment was slight, necessitating ar
tificial detachment. Of the 26 eyes, 20 experienced iatrogenic retinal
breaks and 6 (23%) experienced postoperative retinal detachment due t
o iatrogenic breaks. Three cases worsened to anterior proliferative vi
treoretinopathy and retinal reattachment could not be achieved. Conclu
sions: In vitrectomy for PDR with asteroid hyalosis, and in cases of s
imple vitreous hemorrhage, surgery should be performed with full under
standing of the anatomic characteristics. Notably, if posterior Vitreo
us detachment is not present, the occurrence of iatrogenic retinal bre
aks is more likely.