DELAYED HEMOLYTIC TRANSFUSION REACTION DUE TO ANTI-M ANTIBODY

A female patient with delayed haemolytic transfusion reaction due to a nti-M antibody is described, Diagnosis was based on laboratory evidenc e of haemolysis and on characteristic serological findings. Anti-hi wa s detected in the recipient's serum 7 d after the last transfusion epi sode. This alloantibody had not been present in the pretransfusion ser um. In addition, the direct antiglobulin test was positive on post-tra nsfusion testing and the implicated antibody was eluted from post-tran sfused red cells. Delayed haemolytic transfusion reactions have long b een recognized as a potential hazard of transfusion therapy, but such cases due to anti-M are extremely rare.