FACILE FORMATION OF N-ALKYL-OXAZOLIDIN-2-ONES FROM N-ALKYL-NITROXYETHYLAMINES AND CARBONATE ANION IN BIPHASIC MEDIA

Authors
SITZMANN ME KENAR JA TRIVEDI NJ
Citation
Me. Sitzmann et al., FACILE FORMATION OF N-ALKYL-OXAZOLIDIN-2-ONES FROM N-ALKYL-NITROXYETHYLAMINES AND CARBONATE ANION IN BIPHASIC MEDIA, Tetrahedron letters, 39(45), 1998, pp. 8211-8212
Citations number
2
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
45
Year of publication
1998
Pages
8211 - 8212
Database
ISI
SICI code
0040-4039(1998)39:45<8211:FFONFN>2.0.ZU;2-Y
Abstract
Nitration of N-alkyl ethanolamines (1) followed by treatment of their corresponding N-alkyl-N-(2-nitroxyethyl)amine salts (2) in a biphasic CH2Cl2/aqueous Na2CO3 or NaHCO3 mixture at 25 degrees C gives N-alkyl- oxazolidin-2-ones (3). This represents a new method that allows the pr eparation of oxazolidinones at ambient temperature with the use of aqu eous carbonate. Published by Elsevier Science Ltd.