Isatoic anhydride(1) can be attached to Merrifield resin by alkylation
on its nitrogen. A maximum loading of 3.2 mmol of anhydride/g of 5 wa
s achieved. This resin, due to the highly reactive anhydride moiety, c
ompletely removes primary and secondary aliphatic amines from reaction
s where they are used in excess. (C) 1998 Elsevier Science Ltd. All ri
ghts reserved.