A REVERSIBLE AFFINITY TAG FOR THE PURIFICATION OF N-GLYCOLYL CAPPED PEPTIDES

Authors
SHOGRENKNAAK MA IMPERIALI B
Citation
Ma. Shogrenknaak et B. Imperiali, A REVERSIBLE AFFINITY TAG FOR THE PURIFICATION OF N-GLYCOLYL CAPPED PEPTIDES, Tetrahedron letters, 39(45), 1998, pp. 8241-8244
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
45
Year of publication
1998
Pages
8241 - 8244
Database
ISI
SICI code
0040-4039(1998)39:45<8241:ARATFT>2.0.ZU;2-9
Abstract
A reversible biotin affinity tag, 2-[N-(Biotin)-6-aminocaproate]-aceta te (1), has been generated for the efficient purification of peptides requiring N-terminal derivatization. This methodology is compatible wi th solid phase peptide synthesis techniques. (C) 1998 Elsevier Science Ltd. All rights reserved.